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The predictive value of serum vascular endothelial growth factor in response to transarterial chemoembolisation in hepatocellular carcinoma / Ahmed Mokhtar Sllam ; Supervised Nasr Mohammed Allahloubi , Abdelrahman Nabawy Zekri , Hanan Ramadan Nassar

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Ahmed Mokhtar Sllam , 2015Description: 216 P. : facsimiles ; 30cmOther title:
  • القيمة التنبؤية لعامل نمو بطانة الأوعية فى المصل تأثرا بالحقن الكيميائى السدى للشريان الكبدى عن طريق القسطرة فى سرطان الكبد [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology - Medical Summary: In the current study 63 newly diagnosed HCC patients were recruited, between June 2012 and June 2013. 35 of them underwent TACE as a primary treatment modality (group A), while 28 of them (group B) were not candidates for immediate TACE. VEGF serum levels were measured using ELISA on days 0, 4, and 30 of TACE in group A, and days 0, 4, and 30 of recruitment in group which was considered a control group to assess potential variation of VEGF over time in the non-intervention group. VEGF serum level was found to correlate with advanced HCC tumor stage, with the higher levels observed in patients with more advanced disease. VEGF serum levels (baseline, day 4,and day 30) were also found to be predictive for PFS, OS, and response in HCC patients treated by TACE. Higher levels were associated with worse outcome
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.04.Ph.D.2015.Ah.P (Browse shelf(Opens below)) Not for loan 01010110068595000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.04.Ph.D.2015.Ah.P (Browse shelf(Opens below)) 68595.CD Not for loan 01020110068595000

Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology - Medical

In the current study 63 newly diagnosed HCC patients were recruited, between June 2012 and June 2013. 35 of them underwent TACE as a primary treatment modality (group A), while 28 of them (group B) were not candidates for immediate TACE. VEGF serum levels were measured using ELISA on days 0, 4, and 30 of TACE in group A, and days 0, 4, and 30 of recruitment in group which was considered a control group to assess potential variation of VEGF over time in the non-intervention group. VEGF serum level was found to correlate with advanced HCC tumor stage, with the higher levels observed in patients with more advanced disease. VEGF serum levels (baseline, day 4,and day 30) were also found to be predictive for PFS, OS, and response in HCC patients treated by TACE. Higher levels were associated with worse outcome

Issued also as CD

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