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Formulation of multi-unit tablets combining pulsatile and sustained effects of a model drug / Kirolos Raafat Habib Georgy ; Supervised Ehab Rasmy Bendas , Randa Latif Aziz , Ragwa Mohamed Farid

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Kirolos Raafat Habib Georgy , 2019Description: 197 P. : charts ; 25cmOther title:
  • تشكيل أقراص متعدده الوحدات تجمع بين التأثيرين النابض والممتد لنموذج دوائي [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics Summary: Oral drug delivery is the most convenient route of drug administration. More efforts were performed to optimize this route for therapeutic maximization and side effects minimization. Controlled drug delivery was developed to enhance drug performance and increase patient compliance. There are several factors affecting the anticipation of developing oral modified release systems. Such factors are either drug or polymer related. The aim of the present work is to formulate and evaluate controlled release oral dosage forms of etodolac through the manipulation of different formulation parameters to achieve the optimized formulation owning pulsatile and sustained drug delivery. Etodolac was formulated with different polymers (EudragitP® P and HPMC) at different ratios
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.08.M.Sc.2019.Ki.F (Browse shelf(Opens below)) Not for loan 01010110078695000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.08.M.Sc.2019.Ki.F (Browse shelf(Opens below)) 78695.CD Not for loan 01020110078695000

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics

Oral drug delivery is the most convenient route of drug administration. More efforts were performed to optimize this route for therapeutic maximization and side effects minimization. Controlled drug delivery was developed to enhance drug performance and increase patient compliance. There are several factors affecting the anticipation of developing oral modified release systems. Such factors are either drug or polymer related. The aim of the present work is to formulate and evaluate controlled release oral dosage forms of etodolac through the manipulation of different formulation parameters to achieve the optimized formulation owning pulsatile and sustained drug delivery. Etodolac was formulated with different polymers (EudragitP® P and HPMC) at different ratios

Issued also as CD

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