Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Coarctation of aorta (CoA) is a common birth defect that account for 5-8% of congenital heart diseases with variable management strategies. Objective: to study the results of CoA repair by surgery or trans catheter balloon angioplasty(BA) to find the best intervention modality according to age. Methodology: cross-sectional study was conducted in Cairo University Children Hospital in the period from March 2005 to August 2018. The medical records of the patients were reviewed including patient age, presenting manifestations, age of intervention, type of intervention, post-intervention complications, laboratory finding including e-GFR and transthoracic color Doppler echocardiography, preintervention and post intervention follow up. Results: From a total of 115 studied cases, 107 (93%) were proved to have surgical repair. About 75 % of them were below one year old. Surgery as an initial treatment prevents the progress of heart failure beyond NYHA class I in 70% of cases. About 29 % of patients had blood pressure measurement above 95th percentile for age and gender with more susceptibility to post intervention hypertensive in trans catheter treated cases. Recoarctation is more common with balloon angioplasty (BA) (75%) than for surgery (53%). Postoperative complications included re-coarctation (88.3 %), high blood pressure (31.3%), absent peripheral pulsations (51.9 %) and infections (10.4%). Conclusion: surgery is a commonly used management strategy in CoA repair. systemic hypertension and re-coarctation are a common findings after CoA intervention

Issued also as CD