Thesis (M.Sc.) - Cairo University - Faculty of Dentistry - Department of Operative dentistry

The current study was conducted to compare and evaluate the effects of a new Fluoride varnish containing Chlorhexidine (CHX) and Cetylpyridinium Chloride (CPC) and a conventional Fluoride varnish on dental plaque and streptococcus mutans count in high caries risk patients. Methodology: Thirty-Four high caries risk patients received randomly two types of varnishes, either Fluoride varnish containing CHX and CPC (Cervitec F) or conventional Fluoride varnish (Flour Protector) as an active control. Dental plaque index (PI) and digital image analysis (AI) to disclosed plaque as well as mutans streptococci count recording were performed at baseline before the application and at 2nd, 4th, 12th, and 24th week of the study in the morning before teeth brushing. Results: For the Plaque index and image analysis for dental plaque, both varnishes showed a statistically significant reduction in the mean of dental plaque between baseline and all follow-ups. On the other hand, Cervitec F (Fluoride varnish containing CHX and CPC) was found to be more effective than Fluor Protector (conventional Fluoride varnish) but the difference was not significant. For plaque bacterial count, both varnishes showed a statistically significant reduction in the mean of streptococcus mutants count between the baseline and all follow-ups. While the Cervitec F varnish achieved a statistically significant reduction in streptococcus mutants count more than what was seen in the Fluor Protector group. Conclusion: Under the limitation of the current study the following conclusion can be mentioned: (1) Both Conventional Fluoride varnish and Fluoride varnish with CHX and CPC can decrease bacterial load and plaque accumulation. (2) Fluoride varnish with CHX and CPC achieved a more reduction in streptococcus mutants count compared to the Conventional Fluoride varnish group. (3) Re-application of vanishes every 3 months is preferred for high caries risk patients for better plaque and bacterial control.

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