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Synthesis of certain 8 - quinolyloxy and / or carbocyclic nitrogenous compounds for microbiological testing /

Madlen Berty Labib Wanas

Synthesis of certain 8 - quinolyloxy and / or carbocyclic nitrogenous compounds for microbiological testing / تشييد بعض مشتقات نيتروجينية تحوى مجموعة 8 - كينوليلوكسى و / او حلقات متجانسة للاختبار الميكروبيولوجى Madlen Berty Labib Wanas ; Supervised Mervat Mustafa ElEnany , Samiha Mohamed Ali Roshdy , Ossama Metwally ElBadry - Cairo : Madlen Berty Labib Wanas , 2006 - 128 Leaves : ill ; 30cm

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Organic Chemistry

The present thesis comprises a survey covering the biological importance of 8 - hydroxyquinolines and the carbocyclic p - aminobenzoic acid and salicylic acid derivatives The study involves esterification of p - aminobenzoic acid with ethanol to give benzocaine (I) which was diazotized then reacted with salicylic acid to yield the azo derivative IIHydrazinolysis of the ester II resulted in the hydrazide IIICondensation of the latter with some aromatic carbonyl compounds afforded the arylidene derivatives IVa - lAlso , reacting the hydrazide III with certain acid anhydrides led to the substituted amide derivatives Va - c



Carbocyclic nitrogenous Microbiological testing Organic Chemistry