Synthesis, Radioprotective and anticancer activity of some novel pyrazolo [3,4-d] pyrimidines /
Sarah Ahmed Mohamed Aboulmagd
Synthesis, Radioprotective and anticancer activity of some novel pyrazolo [3,4-d] pyrimidines / تشييد وتحضير بعض مركبات البيرازولو (4.3-د) بيريميدين الجديدة كمضادات الاورام السرطانية وكواقيات من الاشعاع Sarah Ahmed Mohamed Aboulmagd ; Supervised Fatma Abdelfattah Ragab , Mostafa Mohamed Soliman Ghorab - Cairo : Sarah Ahmed Mohamed Aboulmagd , 2009 - 119 P. : charts ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry
Substituted pyrazolo [3,4-d] pyrimidine derivatives have been reported to show anticancer and antileukemic activity, in addition to radioprotective activity. Different mechanisms account for the cytotoxic effect of this class of compounds, where they have been reported to act as tyrosine kinase inhibitors and potent axonthine oxidase inhibitors
Anticancer activity Pyrazolo [3,4-d] pyrimidines Radiorotective activity
Synthesis, Radioprotective and anticancer activity of some novel pyrazolo [3,4-d] pyrimidines / تشييد وتحضير بعض مركبات البيرازولو (4.3-د) بيريميدين الجديدة كمضادات الاورام السرطانية وكواقيات من الاشعاع Sarah Ahmed Mohamed Aboulmagd ; Supervised Fatma Abdelfattah Ragab , Mostafa Mohamed Soliman Ghorab - Cairo : Sarah Ahmed Mohamed Aboulmagd , 2009 - 119 P. : charts ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry
Substituted pyrazolo [3,4-d] pyrimidine derivatives have been reported to show anticancer and antileukemic activity, in addition to radioprotective activity. Different mechanisms account for the cytotoxic effect of this class of compounds, where they have been reported to act as tyrosine kinase inhibitors and potent axonthine oxidase inhibitors
Anticancer activity Pyrazolo [3,4-d] pyrimidines Radiorotective activity