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Clinical applications of ex vivo expanded hematopoietic stem and progenitor cells /

Riham Ali Gad

Clinical applications of ex vivo expanded hematopoietic stem and progenitor cells / الاستخدامات العملية لخلايا الدم الجذعية والاولية المتكاثرة خارج الجسم Riham Ali Gad ; Supervised Omayma Goher , Doha Abd El hameed - Cairo : Riham Ali Gad , 2005 - 122P ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty Of Medicine - Department Of Clinical and Chemical Pathology

It has been hypothesized that the capacity to expand in vitro the quantity of hematopoietic stem and progenitor cells available for transplantation would enhance hematopoietic engraftment , reduce the risk of infection , so increasing the number of potentially available alternative donors Moreover , successful ex vivo expansion of hematopoietic stem cells could be used in many clinical applications , including tumor purging , increasing number of cells available for genetic modification , and generating large quantities of immunologically reactive cells for adoptive immunotherapy



Bone marrow transplantation ex vivo expansion hematopoietic stem cells