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Pharmacological studies of the effect of captopril celecoxib and their combination on an expreimental animal model of lung fibrosis /

Rehab Ragab Hegazy Mohamed Hegazy

Pharmacological studies of the effect of captopril celecoxib and their combination on an expreimental animal model of lung fibrosis / دراسات فارماكولوجية لتاثير كابتوبريل وسيليكوكسيب عند استخدام كل على حدة ومعا فى نموذج لتليف الرئة فى حيوانات التجارب Rehab Ragab Hegazy M. Hegazy ; Supervised Sanaa A. Kenawy , Ola A. Sharaf - Cairo : Rehab Ragab Hegazy Mohamed Hegazy , 2008 - 185P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology

The present study has been constructed to investigate the possible protective effect of captopril and celecoxib when used alone or in combination against pulmonary fibrosis induced in rats by blecomycin (BLM) . It was found that BLM (15 mg/kg i. p. 3 times / week) induced lung fibrosis in rats following 4 successive week of administration



Blecomycin Captopril Lung fibrosis