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Pharmaceutical study of polymorphic transformation of praziquantel /

Amal Anwar Taha

Pharmaceutical study of polymorphic transformation of praziquantel / دراسة صيدلية على تحول الشكل البلورى لعقار البرازيكوانتيل Amal Anwar Taha ; Supervised Ahmed Abdelbary , Mohamed A. Nafadi - Cairo : Amal Anwar Taha , 2009 - 214 P. : charts ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics

The work in this thesis focused on two issues. The first issue is to study the effect of recrystallization of praziquantel (PZQ) from different solvents, and in the presence of different additives on PZQ crystal habit and detecting the possibility of appearance of new polymorphs. The second issue is to investigate the effect of the recrystallization process on solubility and dissolution characteristics of PZQ aiming to improve its bioavailability



Polymorphism Praziquantel Recrystallization