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Effect of low - dose l - thyroxine and lacidipine as vasodilators on the microcirculation in systemic lupus erythematosus /

Moustafa Kamel Eltomy

Effect of low - dose l - thyroxine and lacidipine as vasodilators on the microcirculation in systemic lupus erythematosus / تأثير دوائى ال - ثيروكسين ولا سيديبين كموسعات للأوعية على الدورة الدموية الدقيقة فى مرض الذئبة الاحمرارية Moustafa Kamal Eltomy ; Supervised Ali Mamdouh Elashmoui , Gaafar Mohamed Ragab , Mervat Elansary - Cairo : Moustafa Kamel Eltomy , 2006 - 141P : facsimiles ; 25cm

Thesis (PH.D.) - Cairo University - Faculty Of Medicine - Department Of Internal Medicine

The effect of L - thyroxine (25 g) and lacidipine (2 mg) on the microcirculation in SLE patients was studied by comparing pre - and post - treatment laser Doppler flow (LDF) parameters We found that the drugs caused impairment of LDF measures This can be attributed to endothelial dysfunction , platelet activation , or asteal phenomenon A significant negative correlation of platelet count and LDF parameters was observed



Doppler Laser SLE