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Adriamycin induced cardiotoxicity and the possible protective role of silymarin in adult male albino rat : A light and electron microscopic study /

Ramadan Moustafa Elsayed

Adriamycin induced cardiotoxicity and the possible protective role of silymarin in adult male albino rat : A light and electron microscopic study / التأثير السمى لعقار الأدرياميسين على قلب الفأر الأبيض البالغ والدور الوقائى المحتمل للسيليمارين : دراسة بالمجهر الضوئى والألكترونى Ramadan Moustafa Elsayed ; Supervised Helana Labib Mitry , Tarek Abdelmoniem Abdelsalam , Ehab Abdelaziz Ahmed - Cairo : Ramadan Moustafa Elsayed , 2010 - 114 P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Anatomy

Adriamycin is a potent anticancer agent its clinical use is associated with cardiotoxicity . The present study aimed investigate the possible protective role of the natural antioxidant silymarin on Adriamycin induced heart toxicity . The cardiotoxicity of Adriamycin was manifested by elevated cardiac enzymes ( LDH and CPK ) and increased serum cholesterol and triglycerides



Adriamycin Antioxidant Cardiotoxicity