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Safety and efficcacy of plasmid mediated thromboietin gene therapy in the treatment of thrombocytopenia secondary to chronic liver disease /

Khalid Hassan Elsherif

Safety and efficcacy of plasmid mediated thromboietin gene therapy in the treatment of thrombocytopenia secondary to chronic liver disease / علاج نقص الصفائح الدموية الناتج عن أمراض الكبد المزمنة عن طريق حقن جين الثرومبوبويتين Khalid Hassan Elsherif ; Supervised Laila Ahmed , Hosny Salama , Wafaa Elmetenawy - Cairo : Khalid Hassan Elsherif , 2010 - 149P. : charts ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine

Thrombocytopenia is a common complication in patients with chronic liver disease it occurs in about 76% in cirrhotic patients . Thrombocytopenia secondary to chronic liver disease is mainly due to ; Thrombopoiein deficiency , hypersplenism, bone marrow suppression and autoimmune mechanism



Hypersplenism Thrombopoiein TPO gene therapy