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A retrospective study of L- asparaginase induced thrombosis in pediatric acute lymphoblastic leukemia patients /

Omar Shawki Farid Arafah

A retrospective study of L- asparaginase induced thrombosis in pediatric acute lymphoblastic leukemia patients / دراسة ارتجاعية عن التخثر الدموى الناتج عن عقار الاسباراجينيز فى الاطفال المصابين بسرطان الدم الليمفاوى الحاد Omar Shawki Farid Arafah ; Supervised Iman Abdelmokhales Sidhom , Iman Mohamed Zaki , Ahmed Mohamed Kamel - Cairo : Omar Shawki Farid Arafah , 2009 - 222P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Pediatric Oncology

Thromboembolism yTE is a well recognized serious complication in association with ALL leading to significant morbidity . Development of TE does interfere with the scheduled treatment plan for ALL and thus ultimate outcome from ALL .Concomitant administration of asparaginase and steroids is likely to be associated with higher incidence of TE especially in children with at least one prothrombotic risk factor



Acute lymphoblastic leukemia Asparaginase Thromboembolism