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Pharmaceutical studies on improvement of solubility dissolution and bioavailability of an insoluble drug /

Mona Hassan Mohamed Aburahma

Pharmaceutical studies on improvement of solubility dissolution and bioavailability of an insoluble drug / دراسات صيدلية عن تحسين الذوبان و صفات الاذابة و التوافر الحيوى لدواء شحيح الذوبان فى الماء Mona Hassan Mohamed Aburahma ; Supervised Yassein Elsaid Hamza , Hanan Mohamed Ellaithy - Cairo : Mona Hassan Mohamed Aburahma , 2007 - 241P. : charts ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty Of Pharmacy - Department Of Pharmaceutics

Vinpocetine a poorly - water soluble drug is widely used for treatment of disorders arising from cerebrovascular and cerebral degenerative diseases.However its oral formulations exhibit very poor and variable bioavailability owing to its reduced aqueous solubility and manifested hepatic first pass metabolism



Self - microemulsifying drug delivery systems Sublingual porous tablets Vinpocetine