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Effect of inhibition of nitric oxide synthase and cyclooxygenase -2 on transient global ischemia - induced damage in rats /

Sarah Ahmed Abdelaal Ahmed

Effect of inhibition of nitric oxide synthase and cyclooxygenase -2 on transient global ischemia - induced damage in rats / تأثير انخفاض نشاط كل من الانزيم المصنع لاكسيد النيتريك وسيكلو او كسيجنيز -2 فى التلف المحدث نتيجة احتباس الدم الشامل والعابر فى الجرذان Sarah Ahmed Abdelaal Ahmed ; Supervised Sanaa A. Kenawy , Mona Seif Elnasr , Maha M. Elsawalhi - Cairo : Sarah Ahmed Abdelaal Ahmed , 2011 - 181P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology

Trasient global cerebral ischemia (TGCI) is a clinical outcome occurring as a consequence of conditions like cardiac arrest coronary artery bypass surgery and reversible severe hypotension . The pyramidal neurons of the CA1 regin in the hippocampus are among the vulnerable cell to loss of blood supply to the brain



CA1 DND Global cerebral ischemia