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Interleukin -3 receptor alpha chain as a unique marker for leukemic stem cells in acute non- lymphatic leukemia /

Fatma Abdalhafiz Mohamed Alrefaie

Interleukin -3 receptor alpha chain as a unique marker for leukemic stem cells in acute non- lymphatic leukemia / سلسلة الفا لمستقبل الانترلوكين -3 كعلامة فريدة للخلايا الجذعية السرطانية فى اللوكيميا الحادة الغير ليمفاوية Fatma Abdalhafiz Mohamed Alrefaie ; Supervised Amira Mokhtar Khorshid , Khaled Mostafa Aboulenein , Osman Mohamed Mansour - Cairo : Fatma Abdalhafiz Mohamed Alrefaie , 2011 - 196 P. : charts , facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Clinical Pathology

Recent studies suggest that the population of malignant cells found in human acute myeloid leukemia (AML) arises from a rare population of leukemic stem cells (LSCs) Flow cytometric studies using bone marrow of newly diagnosed AML patients showed that the interleukin -3 receptor alpha chain was strongly expressed in (91.7%) of primary specimens and (90%) of post culture specimens



AML Leukemia Stem cell