Pharmacognostical study of mimusops laurifolia cultivated in Egypt : Family sapotaceae /
Mai Mohamed Hasan Raslan
Pharmacognostical study of mimusops laurifolia cultivated in Egypt : Family sapotaceae / دراسة عقاقيرية لنبات الميموسوبس لاوريفوليا المنزرع فى مصر : العائلة سابوتيسى Mai Mohamed Hasan Raslan ; Supervised Mohamed S. Hifnawy , Nadia M. Sokkar , Shahira M. Ezzat - Cairo : Mai Mohamed Hasan Raslan , 2011 - 198 P. : charts ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacognosy
Fourteen compounds were isolated for the first time from the leaves of Mimusops laurifolia (Forssk.) Friis based on bioassay guided fractionation. The leaves ethanolic extract and its different fractions were evaluated for their cytotoxic activities against human liver cancer cell line (HEPG2), the highest activity was exhibited by the n-hexane fraction (IC50 14.4 og/ml) from which three triterpenes, namely; lupeol acetate, Ü-amyrin and oleanolic acid and two sterols, namely; chondillasterol and its 3-O-galactoside were isolated for the first time
Anticancer Hepatoprotective Mimusops laurifolia
Pharmacognostical study of mimusops laurifolia cultivated in Egypt : Family sapotaceae / دراسة عقاقيرية لنبات الميموسوبس لاوريفوليا المنزرع فى مصر : العائلة سابوتيسى Mai Mohamed Hasan Raslan ; Supervised Mohamed S. Hifnawy , Nadia M. Sokkar , Shahira M. Ezzat - Cairo : Mai Mohamed Hasan Raslan , 2011 - 198 P. : charts ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacognosy
Fourteen compounds were isolated for the first time from the leaves of Mimusops laurifolia (Forssk.) Friis based on bioassay guided fractionation. The leaves ethanolic extract and its different fractions were evaluated for their cytotoxic activities against human liver cancer cell line (HEPG2), the highest activity was exhibited by the n-hexane fraction (IC50 14.4 og/ml) from which three triterpenes, namely; lupeol acetate, Ü-amyrin and oleanolic acid and two sterols, namely; chondillasterol and its 3-O-galactoside were isolated for the first time
Anticancer Hepatoprotective Mimusops laurifolia