Ostcopontin gene polymorphism as marker predicting the efficacy of interferon-based therapics in patients with chronic hepatitis C /
Rehab Mustafa Abdelfadel
Ostcopontin gene polymorphism as marker predicting the efficacy of interferon-based therapics in patients with chronic hepatitis C / التحور فى جين الاستيوبونتين كدلالة لتوقع كفائه العلاج بالانترفيرون فى مرضى الالتهاب الكبدى المزمن سى Rehab Mustafa Abdelfadel ; Supervised Olfat Gamil Shaker , Amr Aly Zahra , Salwa Fayez Hasan - Cairo : Rehab Mustafa Abdelfadel , 2011 - 99 P. : charts ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry
Viral hepatitis is T cell-mediated and ostcopontin induce T cell chemotaxis, support adhesion, proliferation, and also enhance expression of T helper 1 (Th1) cytokines. Genetic polymorphisms in the ostcopontin gene (OPN) determine the magnitude of immunity against rickettsial infection in mice. Similar polymorphisms, if present also in human beings, might affect hepatitis activity and the response to treatment by interferon and ribavirin in those infected with HCV
HCV Interferon Ostcopontin
Ostcopontin gene polymorphism as marker predicting the efficacy of interferon-based therapics in patients with chronic hepatitis C / التحور فى جين الاستيوبونتين كدلالة لتوقع كفائه العلاج بالانترفيرون فى مرضى الالتهاب الكبدى المزمن سى Rehab Mustafa Abdelfadel ; Supervised Olfat Gamil Shaker , Amr Aly Zahra , Salwa Fayez Hasan - Cairo : Rehab Mustafa Abdelfadel , 2011 - 99 P. : charts ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry
Viral hepatitis is T cell-mediated and ostcopontin induce T cell chemotaxis, support adhesion, proliferation, and also enhance expression of T helper 1 (Th1) cytokines. Genetic polymorphisms in the ostcopontin gene (OPN) determine the magnitude of immunity against rickettsial infection in mice. Similar polymorphisms, if present also in human beings, might affect hepatitis activity and the response to treatment by interferon and ribavirin in those infected with HCV
HCV Interferon Ostcopontin