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Formulation and evaluation of controlled release dosage forms for a central nervous system acting drug /

Ibrahim Elsayed Mohamed Hassan

Formulation and evaluation of controlled release dosage forms for a central nervous system acting drug / صياغة وتقييم أشكال صيدلية منضبطة الانطلاق لعقار يعمل على الجهاز العصبى المركزى Ibrahim Elsayed Mohamed Hassan ; Supervised Soad A. Yehia , Ahmed H. Elshafeey - Cairo : Ibrahim Elsayed Mohamed Hassan , 2011 - 246 P. : charts , facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics

Alzeimer's disease is a chronic , progressive , neurodegenerative disorder of the brain characterized by deficits in memory and cognitive function . Donepezil is a reversible , noncompetitive cholinesterase inhibitor . Formulation and In Vitro Evaluation of Injectable Donepezil lipospheres . Donepezil HCI lipospheres were prepared using melt dispersion technique



Donepezil In situ implant Lipospheres