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A biopharmaceutical study on a proton pump inhibitor /

Ebtsam Mohammed Abdou Mohammed

A biopharmaceutical study on a proton pump inhibitor / دراسة بيوصيدلية على عقار مثبط لمضخة البروتون Ebtsam Mohammed Abdou Mohammed ; Supervised Mona Hassan Aboulelnien , Nadia Abdelkader Soliman - Cairo : Ebtsam Mohammed Abdou Mohammed , 2012 - 190 P. : charts , facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics

Rabeprazole solium is a potent proton pump inhibitor used to relieve symptoms of gastroesophageal reflux disease (GERD) gastric ulceration and acute upper gastrointestinal bleeding . It is a prodrug which is absorbed unchanged from the intestinal wall then converted to its active form which has inhibitory effect on the ATP -as enzyme in the gastric parietal cells



Bioavailability Disintegrants Rabeprazole