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Pharmacological study of the effect of certain natural products on doxorubicin induced nephropathy in rats exposed to low doses of radiation /

Rasha Radwan Radwan

Pharmacological study of the effect of certain natural products on doxorubicin induced nephropathy in rats exposed to low doses of radiation / دراسة فارماكولوجية لتأثير بعض المنتجات الطبيعية فى الاعتلال الكلوى المحدث بدوكسروبسين فى الجرذان المعرضة لجرعات صغيرة من الإشعاع Rasha Radwan Radwan ; Supervised Sanaa A. Kenawy , Esmaat A. Shaaban , Hesham Aly Salem - Cairo : Rasha Radwan Radwan , 2012 - 184 P. : charts ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology

The possible protective potential of exposure to low dose of radiation in presence or absence of L-carnitine, curcumin, garlic powder or green tea extract was examined in the present study on doxorubicin (DOX)-induced experimental nephropathy in rats. Preliminary study was carried out to select the suitable dose of DOX to induce nephrotoxicity. In the current experiment 5 mg/kg, i.p. was selected as a single dose to induce nephrotoxicity during 15 days



0.3 Gy radiation Doxorubicin L-carnitine