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Metabolic and proliferative effects of insulin signaling contributing to the liver regeneration /

George Nazih Bishara Morcos

Metabolic and proliferative effects of insulin signaling contributing to the liver regeneration / التأثيرات الأيضية والتكاثرية لاشارات هرمون الانسولين المساهمة فى تجديد خلايا الكبد George Nazih Bishara Morcos ; Supervised Mona Sarkis Karas , Hubert E. Blum , Nagwa Kamal Eldin Roshdy - Cairo : George Nazih Bishara Morcos , 2012 - 204P. : charts , facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry

The present work is designed to study the expression level of both IRS - 1 and IRS - 2 in primary mouse hepatoctes ( PMH ) and investigate their kinetics of phosphorylation in response to addition of variable doses of insulin . The present study also involves determination of subcellular localization of both IRS - 1 and IRS - 2 in PMH using confocal microscopy



Insulin signaling IRS - 1 Liver regeneration