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The relevance of Ki67 and p53 to adjuvant hormonal treatment outcome in hormone-dependent postmenopausal breast cancer patients /

Yahia Mahmoud Ismail

The relevance of Ki67 and p53 to adjuvant hormonal treatment outcome in hormone-dependent postmenopausal breast cancer patients / دراسة تأثير عامل ك آي ٦٧و بي ٥٣ على الاستجابة للعلاج الهرمونى المساند فى مريضات سرطان الثدى المعتمد على الهرمون فى فترة ما بعد انقطاع الطمث Yahia Mahmoud Ismail ; Supervised Heba Elzawahry , Nadia Mokhtar , Magdy Mohamed Saber - Cairo : Yahia Mahmoud Ismail , 2012 - 129 P. : charts , facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology-Medical

Breast cancer is a major health problem in Egypt and worldwide. Its prognosis depends not only on tumor stage but also on tumor biology. The latter can be assessed through tumor histology, grade, hormone and HER2 receptors, proliferation markers and molecular subtyping. The aim of this study was to correlate the outcome of horomoce-receptor positive postmenopausal breast cancer patients receiving adjuvant tamoxifen therapy with Ki67 and p53 status



Adjuvant hormonal therapy Breast cancer Tamoxifen