header

Expression of melanoma antigen encoding gene-A3 in acute myeloid leukemia /

Noha Said Semary

Expression of melanoma antigen encoding gene-A3 in acute myeloid leukemia / دراسة للتواجد الجيني الانتيجين (المواد المضاد) للورم الميلانيني (ماج-ايه٣) في حالات سرطان الدم الميلودي الحاد Noha Said Semary ; Supervised Hala Mohammed Farawela , Rania Ahmed Zayed , Manal Mohamed Mahmoud Makhlouf - Cairo : Noha Said Semary , 2012 - 160 P. : charts , facsimiles ; 30cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology

Melanoma antigen encoding gene-A3 (MAGE-A3), also called cancer/testis (CT) antigen, is a member of MAGE-multigene family which is located on the long arm of the X chromosome and its expression can be caused by promoter region demethylation. The MAGE-A3 proteins' functions are unknown but it was found to play a role in cell cycle progression, transcriptional regulation and drug resistance



Acute myeloid leukemia AMI LAAS