header

Study of the possible mechanisms of action of atorvastatin in an air - pouch model of inflammation induced in rats /

Jamal Mohamed Dammona

Study of the possible mechanisms of action of atorvastatin in an air - pouch model of inflammation induced in rats / دراسة الآليات الممكنة لعمل أتورفاستاتين فى نموذج حقيبة الهواء المسببة للالتهاب فى الجرذان Jamal Mohamed Dammona ; Supervised Hisham Attia Awad , Amani Nabil Shafik , Mostafa Mahmoud Khodeir - Cairo : Jamal Mohamed Dammona , 2012 - 137P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pharmacology

Statins exert favorable effects on lipoprotein metabolism but may also possess anti - inflammatory effects . Several reports have described the ability of statins to suppress acute and chronic inflammations . The aim of this study was to determine the anti - inflammatory effect of atorvastatin in the rat air - pouch model of inflammation and whether its action is on mevalonate pathway , affecting vascular permeability or beta receptors regulation



Anti - inflammatory Atorvastatin Mevalonate pathway