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Synthesis of some novel quinazolone derivatives and studying their combined anticancer effect with Þ - radiation /

Ahmed Abdelhamid Bayomi

Synthesis of some novel quinazolone derivatives and studying their combined anticancer effect with Þ - radiation / تحضير بعض مشتقات الكينازولون الجديدة ودراسة التأثير التداخلى مع أشعة جاما كمضادات الأورام السرطانية Ahmed Abdelhamid Bayomi ; Supervised Fatma Abdelfattah Ragab , Mostafa Mohamed Ghorab - Cairo : Ahmed Abdelhamid Bayomi , 2012 - 137P. : charts ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry

24 New quinazolone and triazoloquinazolone derivatives bearing sulfapyridine moiety were synthesized . The structure of the newly synthesized compounds were confirmed by elemental analyses and spectral data (IR, ¹H - NMR and mass spectroscopy) . The newly synthesized compounds were subjected to in vitro anticancer screening against human liver cancer cell line (HEPG2) and showed anticancer activity



Derivatives and studying Novel quinazolone Þ - radiation