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Monocytes expression of soluble VEGF receptor-1 (sFLT-1) in patients with sickle cell nephropathy /

Eman Fathy Ahmed Behary

Monocytes expression of soluble VEGF receptor-1 (sFLT-1) in patients with sickle cell nephropathy / تعبير الخلايا وحيدة النواة عن عامل نمو بطانة الأوعية الدموية الذائب في مرضى اعتلال الكلية المنجلي Eman Fathy Ahmed Behary ; Supervised Manal Michel Wilson , Rania Fawzy Hammoud . Ilham Youssry Ibrahim - Cairo : Eman Fathy Ahmed Behary , 2012 - 123 P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology

The anti-angiogenic factor soluble fms-like tyrosine kinase-1 (sFLT-1) is a member of the vascular endothelial growth factor receptor (VEGFR) family. sFLT-1 is produced due to misregulation of fms-like tyrosine kinase in the endothelial cells and the peripheral blood mononuclear cells resulting in over expression of the soluble splice variant of FLT-1 in the plasma and mononuclear cells



Sickle nephropathy Soluble fms-like tyrosine kinase-1 Vascular endothelial growth factor receptor