Novel delivery of oseltamivir phosphate dry powder inhalation-formulation and in-vitro characterization /
Shahir Ashraf Wagdy Aziz
Novel delivery of oseltamivir phosphate dry powder inhalation-formulation and in-vitro characterization / Shahir Ashraf Wagdy Aziz ; Supervised Hanan M. Ellaithy - Cairo : Shahir Ashraf Wagdy Aziz , 2011 - 111LEaves : charts , facsimiles ; 30cm
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmacology and Toxicology
Oseltamivir phosphate (OP) is an antiviral drug available only as oral therapy for the treatment of Influenza . The aim of this work is to formulate OP as a dry powder inhalation (DPI) using a novel developed inhaler device (UNI-Haler) for faster targeting and more efficient therapy . Micronized (0.5-5om) and milled (17-45om) Lactose , Trehalose , Mannito and Glucose were used as inert carriers for the preparation of OP DPI formulations
Novel delivery of oseltamivir phosphate dry powder inhalation-formulation and in-vitro characterization / Shahir Ashraf Wagdy Aziz ; Supervised Hanan M. Ellaithy - Cairo : Shahir Ashraf Wagdy Aziz , 2011 - 111LEaves : charts , facsimiles ; 30cm
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmacology and Toxicology
Oseltamivir phosphate (OP) is an antiviral drug available only as oral therapy for the treatment of Influenza . The aim of this work is to formulate OP as a dry powder inhalation (DPI) using a novel developed inhaler device (UNI-Haler) for faster targeting and more efficient therapy . Micronized (0.5-5om) and milled (17-45om) Lactose , Trehalose , Mannito and Glucose were used as inert carriers for the preparation of OP DPI formulations