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The effect of low - dose hydrocortisone on requirement of norepinephrine and lactate clearance in patients with refractory septic shock /

Abdalaziz Mostafa Abdalziz Zahran

The effect of low - dose hydrocortisone on requirement of norepinephrine and lactate clearance in patients with refractory septic shock / تأثير الجرعات المنخفضة من عقار الهيدروكورتيزون على جرعات النورابينفرين ونسبة اللاكتات بالدم فى مرضى الصدمة البكتيرية الغير مستجيبة للعلاج التقليدى Abdalaziz Mostafa Abdalziz Zahran ; Supervised Hesham Alaassar , Sameh Elmaraghi , Ayman Heikal - Cairo : Abdalaziz Mostafa Abdalziz Zahran , 2012 - 154P. : charts , facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Critical Care Medicine

Cortisol is necessary to survive critical but absolute adrenal insufficiency is rare among critically ill patients . However many observations argue that suboptimal cortisol production may be common and associated with worse outcomes . Suboptimal cortisol production during septic shock has been termed functional or relative adrenal insufficiency . In the 1990 s interest in corticosteroids as a therapy in septic shock was renewed this time using smaller more physiological doses for longer duration



Hydrocortisone Refractory septic shock Serum lactate
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