Glypican 3 as a novel marker for Hepatocellular carcinoma /
Alice Saber Gerges
Glypican 3 as a novel marker for Hepatocellular carcinoma / الجليبكان 3 كدلالة جديدة للورم السرطانى بالكبد Alice Saber Gerges ; Supervised Inas Ismail Raafat , Eman El-Ghroury , Mai Mahmoud Sherif - Cairo : Alice Saber Gerges , 2013 - 180 P. : charts ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
Most of patients with HCC are diagnosed at a late stage. Therefore, the prognosis of HCC patients is generally very poor. Alpha.fetoprotein has been widelly used , but its sensitivity has not been satisfactory , in addition to its non-specific elevation innon malignant hepatic diseases. Glypican 3, this protein(GPC3) is over-expressed in HCC, and not in normal hepatocytes and non-malignant liver disease.
Glypican 3 Hepatocellular carcinoma Real time PCR
Glypican 3 as a novel marker for Hepatocellular carcinoma / الجليبكان 3 كدلالة جديدة للورم السرطانى بالكبد Alice Saber Gerges ; Supervised Inas Ismail Raafat , Eman El-Ghroury , Mai Mahmoud Sherif - Cairo : Alice Saber Gerges , 2013 - 180 P. : charts ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
Most of patients with HCC are diagnosed at a late stage. Therefore, the prognosis of HCC patients is generally very poor. Alpha.fetoprotein has been widelly used , but its sensitivity has not been satisfactory , in addition to its non-specific elevation innon malignant hepatic diseases. Glypican 3, this protein(GPC3) is over-expressed in HCC, and not in normal hepatocytes and non-malignant liver disease.
Glypican 3 Hepatocellular carcinoma Real time PCR