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Effect of mefloquine in murine schistosomiasis mansoni as a prophylactic and chemotherapeutic agent compared to praziquantel /

Shaimaa Helmy Elsayed Ismail

Effect of mefloquine in murine schistosomiasis mansoni as a prophylactic and chemotherapeutic agent compared to praziquantel / تأثير المفلوكين على البلهارسيا المعوية فى الفئران كعامل وقائى وعلاجى مقارنة بالبرازيكوانتال Shaimaa Helmy Elsayed Ismail ; Supervised Maisa Mohamed Kamel , Soaad Ismail Hassan , Nagwa Abdelkhalek Talaat Elkhafif - Cairo : Shaimaa Helmy Elsayed Ismail , 2013 - 148 P. : charts , facsimiles , maps ; 25CM

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Parasitology

Schistosomiasis is a chronic debilitating disease that continues to threaten millions of people, and to be the 2nd major parasitic disease worldwide after malaria in term of morbidity, mortality, and prevalence . The treatment and control of human schistosomiasis rely on a single drug, praziquantel (PZQ), that effectively kills adult schistosomes but lacks efficacy against schistosomulae (juvenile schistosomes) a fact that explains low observed cure rates of schistosomiasis



MFQ PZQ Schistosomiasis mansoni