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Fluvastatin as an adjuvant therapy with pegylated interferon and ribavirin in the treatment of chronic hepatitis C virus /

Haitham Ahmed Ali Gabr

Fluvastatin as an adjuvant therapy with pegylated interferon and ribavirin in the treatment of chronic hepatitis C virus / الفلوفاستاتين كعقار مساعد لعقاري الانترفيرون طويل المفعول و الريبافيرين فى علاج الالتهاب الكبدى الوبائى الفيروسي (سى) المزمن Haitham Ahmed Ali Gabr ; Supervised Zakaria A. Salama , Moataz Serry Seyam , Ahmed Fouad Soliman - Cairo : Haitham Ahmed Ali Gabr , 2013 - 288 P. ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine

It could be argued that statins, besides a weak direct antiviral effect, may enhance HCV infectivity of hepatocytes through the decrease in circulating LDL levels and the up-regulation of LDL receptors. This effect of statins might counterbalance the antiviral activity described in the replicon models



Fluvastatin Statins and HCV Treatment of HCV