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Effect of simvastatin on healing of experimentally induced periapical lesions : An in vivo study /

Heba Ahmed Seif Allah Amin Elasfouri

Effect of simvastatin on healing of experimentally induced periapical lesions : An in vivo study / تأثير حقن السيمفاستاتين على الشفاء فى الآفات حول الذروية التجريبية المستحثة : دراسة فى الكائن الحى Heba Ahmed Seif Allah Amin Elasfouri ; Supervised Maged Mohamed Negm , Mohamed Ayad Abdelhamid , Geraldine Mohamed Ahmed - Cairo : Heba Ahmed Seif Allah Amin Elasfouri , 2013 - 105 Leaves : charts , facsimiles ; 30cm

Thesis (Ph.D.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Endodontics

This study aimed to assess the effect of simvastatin on healing of experimentally induced periapical lesions. 2.5 mg/ml and 5 mg/ml simvastatin was injected through the root canals, in experimental group I and II, respectively. The control group was injected with saline. After one week the canals were obturated. The results showed that the use of simvastatin as intracanal medication in cases of periapical lesions can downregulate inflammation, promote periodontal repair and accelerate healing



Intracanal medication Periapical lesions Simvastatin