Expression of sirtuin 1 and its relation to tumor necrosis factor - alpha in psoriatic plaques /
Aya Magdi Ibrahim Alorbani
Expression of sirtuin 1 and its relation to tumor necrosis factor - alpha in psoriatic plaques / إكتشاف السرتوين و علاقته بعامل نخر الأورام ألفا في مرض الصدفية Aya Magdi Ibrahim Alorbani ; Supervised Hoda Mohamed Hussein Rasheed , Mohamed Hussein Medhat Elkomy , Olfat Gamil Shaker - Cairo : Aya Magdi Ibrahim Alorbani , 2014 - 121 Leaves : facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology
Although it is now considered a prototypic Th1/Th17-mediated disease, several gaps still exist in our understanding of the pathogenesis of psoriasis. Sirtuins, a family of seven proteins that have generated huge interest in several fields including dermatology, have been proposed to contribute to the development of inflammatory and hyperproliferative disease. It has been proposed that changes in Sirtuin 1 (SIRT1), through its effect on pro-inflammatory cytokines such as Tumor Necrosis Factor-alpha (TNF-Ü), may contribute to the development of the psoriatic plaque.
Psoriasis Sirtuins Tumor necrosis factor
Expression of sirtuin 1 and its relation to tumor necrosis factor - alpha in psoriatic plaques / إكتشاف السرتوين و علاقته بعامل نخر الأورام ألفا في مرض الصدفية Aya Magdi Ibrahim Alorbani ; Supervised Hoda Mohamed Hussein Rasheed , Mohamed Hussein Medhat Elkomy , Olfat Gamil Shaker - Cairo : Aya Magdi Ibrahim Alorbani , 2014 - 121 Leaves : facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology
Although it is now considered a prototypic Th1/Th17-mediated disease, several gaps still exist in our understanding of the pathogenesis of psoriasis. Sirtuins, a family of seven proteins that have generated huge interest in several fields including dermatology, have been proposed to contribute to the development of inflammatory and hyperproliferative disease. It has been proposed that changes in Sirtuin 1 (SIRT1), through its effect on pro-inflammatory cytokines such as Tumor Necrosis Factor-alpha (TNF-Ü), may contribute to the development of the psoriatic plaque.
Psoriasis Sirtuins Tumor necrosis factor