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Expression of Glut - 1 , c - erbB - 2 , Ki - 67 and p53 in Surface Epithelial Ovarian Neoplasms as Potential Biologic Prognostic Factors /

Asmaa Ibrahim Abdelaziz Salama

Expression of Glut - 1 , c - erbB - 2 , Ki - 67 and p53 in Surface Epithelial Ovarian Neoplasms as Potential Biologic Prognostic Factors / تقييم جلوت - 1 و سى ارب بى - 2 و كى اى - 67 و بى 53 فى اورام الانسجة الطلائية السطحية للمبيض كعوامل بيولوجية محتملة للتنبؤ بمستقبل المرض Asmaa Ibrahim Abdelaziz Salama ; Supervised Mohamed Nabil ElBolkainy , Nayera Anwar Abdelhamid , Mohamed Akram Nouh - Cairo : Asmaa Ibrahim Abdelaziz Salama , 2006 - 250P : ill ; 30cm

Thesis (PH.D.) - Cairo University - National Cancer Institute - Department Of Oncology

All benign tumors were negative to Glut - 1 , c - erbB - 2 , Ki - 67 and p53Neoplasms of LMP were negative to Ki - 67 and lacking c - erbB - 2 overexpressionGlut - 1 overexpression was higher in malignant cases than LMP ones with significant difference (p=0008) c - erbB - 2 overexpression was detected in 344in hundred of malignant casesKi - 67 was detected in 469in hundred of malignant casesp53 overexpression at cut off point 30in hundred was significantly different in LMP cases from malignant onesThere was a trend for shorter DFS in cases whose tumors displayed c - erbB - 2 overexpression (p=0065)



Ki - 67 Ovarian p53