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Role of epidermal growth factor receptor in malignant pleural mesothelioma and its value for successful chemical pleurodesis /

Yasmine Hamdy Elhinnawy

Role of epidermal growth factor receptor in malignant pleural mesothelioma and its value for successful chemical pleurodesis / دور مستقبلات معامل النمو القشر الجلدى فى الميزوثليوما البلورية الخبيثة و قيمته فى إنجاح الالحام الكيمائى للغشاء البلورى Yasmine Hamdy Elhinnawy ; Supervised Ahmed Elhosainy Aly , Hossam Hosny Masoud , Samia Mohamed Gabal - Cairo : Yasmine Hamdy Elhinnawy , 2013 - 160 P. : facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Chest Diseasas and Tuberculosis

The most common primary malignant tumor of the pleura is malignant mesothelioma, it is a highly aggressive tumour that has become a very important issue over recent years. Inhalational exposure to asbestos has been clearly established as the predominant cause of malignant mesothelioma in humans. Approximately 70 percent of cases of pleural mesothelioma are associated with documented asbestos exposure. Evidence suggests that the EGFR is involved in the pathogenesis and progression of different carcinoma types. In vivo and in vitro studies have shown that these proteins are able to induce cell transformation



Epidermal growth factor Malignant pleural mesothelioma Receptor chemical pleurodesis