header

Role of oxidative stress in inducing type {u2160} or type {u2161} diabetes mellitus in Rats /

Shaimaa Mohamed Sayed Kamel

Role of oxidative stress in inducing type or type diabetes mellitus in Rats / دور الإجهاد التأكسدى فى أحداث النوع الأول أو النوع الثانى لمرض البول السكرى فى الفئران Shaimaa Mohamed Sayed Kamel ; Supervised Samy Ahmed Abdelaziz , Hatim Mohamed Ahmed Elhindi , Mohsen Ahmed Wasfy - Cairo : Shaimaa Mohamed Sayed Kamel , 2014 - 140 P. : charts ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Biochemistry and Chemistry of Nutrition

The present study tries to investigate oxidative stress - hyperglycaemia relationship through studying role of ROS and oxidative stress in the pathogenesis of type 2 diabetes mellitus and role of NAC as antioxidant in normalizing these disorders. 200 rats were randomly assigned into four equal groups, 50 rats each; Control group (C) fed on the balanced ration and ordinary drinking water adlibitum. Fructose fed group (F) fed on the balanced ration and fructose 10% (100g/L) in drinking water, fructose and N-acetylcysteine group (FN) fed on the balanced ration and fructose 10% (100g/L) in drinking water for 4 weeks than injected I/P with N- acetylcysteine in dose of 200mg/Kg b.wt



Fructose Insulin resistance Oxidative stress