Synthesis, reactions and characterization of 2- thioxopyridine and their bis-derivatives of expected biological activity /
Hameed Madlool Mohammed Alkubaisi
Synthesis, reactions and characterization of 2- thioxopyridine and their bis-derivatives of expected biological activity / تحضير: تفاعلات وتوصيف مستقات 2-ثيواكسو البيريدين ومشتقاتها الثنائية ذات النشاط البيولوجى المتوقع Hameed Madlool Mohammed Alkubaisi ; Supervised Sadek Elsayed Abdou , Fawzy Ali Attaby , Mohamed A. Elneairy - Cairo : Hameed Madlool Mohammed Alkubaisi , 2014 - 287 P. : harts ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Organic Chemistry
This work has been carried out to investigate the chemical reactivity and synthetic potentiality of 2-thioxohydropyridines via their reaction with several active halogen-containing compounds to afford the corresponding 2- alkylthiopyridines in other cases and thieno[2,3-b]pyridines directly in other cases. Thieno[2,3-b]pyridine-2-carbohydrazides obtained through the reaction of 2-ethoxycarbonylthienopyridines with hydrazine hydrate which in turn, used to obtain the corresponding pyrimidinones, pyrazolothienopyridine derivatives and 1,3,4-oxdiazoles. 3-Aminopyrazolopyridines obtained. The structures of all newly synthesized heterocyclic compounds were elucidated by considering the data of IR, 1H NMR (eppm), mass spectra as well as that of elemental analyses
2-Cyanoethanethioamide 3-carbonitrile Dihydropyridine
Synthesis, reactions and characterization of 2- thioxopyridine and their bis-derivatives of expected biological activity / تحضير: تفاعلات وتوصيف مستقات 2-ثيواكسو البيريدين ومشتقاتها الثنائية ذات النشاط البيولوجى المتوقع Hameed Madlool Mohammed Alkubaisi ; Supervised Sadek Elsayed Abdou , Fawzy Ali Attaby , Mohamed A. Elneairy - Cairo : Hameed Madlool Mohammed Alkubaisi , 2014 - 287 P. : harts ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Organic Chemistry
This work has been carried out to investigate the chemical reactivity and synthetic potentiality of 2-thioxohydropyridines via their reaction with several active halogen-containing compounds to afford the corresponding 2- alkylthiopyridines in other cases and thieno[2,3-b]pyridines directly in other cases. Thieno[2,3-b]pyridine-2-carbohydrazides obtained through the reaction of 2-ethoxycarbonylthienopyridines with hydrazine hydrate which in turn, used to obtain the corresponding pyrimidinones, pyrazolothienopyridine derivatives and 1,3,4-oxdiazoles. 3-Aminopyrazolopyridines obtained. The structures of all newly synthesized heterocyclic compounds were elucidated by considering the data of IR, 1H NMR (eppm), mass spectra as well as that of elemental analyses
2-Cyanoethanethioamide 3-carbonitrile Dihydropyridine