Autologous bone marrow-derived stem cell transplantation in patients with chronic liver diseases /
Ingy Gamal Eldin Elshenawy Mohamed
Autologous bone marrow-derived stem cell transplantation in patients with chronic liver diseases / تأثير زراعة الخلايا الجذعية الذاتية على مرضى أمراض الكبد المزمنة Ingy Gamal Eldin Elshenawy Mohamed ; Supervised Nouman Mohammed Hassaan Elgarem , Mona Ahmed Amin Soliman , Hala Gabr Metwalli - Cairo : Ingy Gamal Eldin Elshenawy Mohamed , 2014 - 159 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Internal Medicine
Liver transplantation is the only current therapeutic modality for liver failure, but due to the shortage of organ donors, it is available to only a small proportion of patients. Adult stem cell therapy could solve the problem of degenerative disorders, including liver disease, in which organ transplantation is inappropriate or there is a shortage of organ donors. This study aimed at evaluating the effect of autologous transplantation of BM-derived mononuclear cells subjected to ex vivo hepatocyte differentiation and BM-derived undifferentiated mesenchymal stem cells in cirrhotic patients, and at assessing the safety and efficacy of transplantation of these cells via direct intrasplenic injection
Chronic liver diseases Liver diseases Stem cell transplantation
Autologous bone marrow-derived stem cell transplantation in patients with chronic liver diseases / تأثير زراعة الخلايا الجذعية الذاتية على مرضى أمراض الكبد المزمنة Ingy Gamal Eldin Elshenawy Mohamed ; Supervised Nouman Mohammed Hassaan Elgarem , Mona Ahmed Amin Soliman , Hala Gabr Metwalli - Cairo : Ingy Gamal Eldin Elshenawy Mohamed , 2014 - 159 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Internal Medicine
Liver transplantation is the only current therapeutic modality for liver failure, but due to the shortage of organ donors, it is available to only a small proportion of patients. Adult stem cell therapy could solve the problem of degenerative disorders, including liver disease, in which organ transplantation is inappropriate or there is a shortage of organ donors. This study aimed at evaluating the effect of autologous transplantation of BM-derived mononuclear cells subjected to ex vivo hepatocyte differentiation and BM-derived undifferentiated mesenchymal stem cells in cirrhotic patients, and at assessing the safety and efficacy of transplantation of these cells via direct intrasplenic injection
Chronic liver diseases Liver diseases Stem cell transplantation