Influence of vitamin D receptor gene polymorphisms on treatment of chronic HCV patients with interferon /
Shymaa Elsayed Ayoub
Influence of vitamin D receptor gene polymorphisms on treatment of chronic HCV patients with interferon / تعدد الاشكال من الجينات لمستقبلات فيتامين د و مدى مستوياته فى الدم فى مرضى الالتهاب الكبدى الوبائى سى المعالجين بالانترفيرون Shymaa Elsayed Ayoub ; Supervised Olfat Gamil Shaker , Yassser Hussein Nassar , Maisa Said Elrazki - Cairo : Shymaa Elsayed Ayoub , 2014 - 99 P. : facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry
Chronic infection with hepatitis C virus (HCV) is a huge problem both globally and at the level of the individual patient. The natural outcome and response to treatment in hepatitis C virus (HCV) infection varies between individuals. Our aim is to detect the Influence of Vitamin D receptor gene polymorphisms (BsmI) and (Fok1) and Vit. D level in the blood of chronic liver disease patients under treatment with interferon. Blood samples were taken from 103 patients who are suffering from chronic hepatitis C disease. They were divided into Respoders (n = 63)and Non- Responders (n = 40)according to their initial response to treatment with normalization of aminotransferases (ALT and AST) levels and clearance of the virus denoted by negative HCV - RNA by PCR after 6 months of receiving treatment
Hepatitis C Polymorphism Vitamin D
Influence of vitamin D receptor gene polymorphisms on treatment of chronic HCV patients with interferon / تعدد الاشكال من الجينات لمستقبلات فيتامين د و مدى مستوياته فى الدم فى مرضى الالتهاب الكبدى الوبائى سى المعالجين بالانترفيرون Shymaa Elsayed Ayoub ; Supervised Olfat Gamil Shaker , Yassser Hussein Nassar , Maisa Said Elrazki - Cairo : Shymaa Elsayed Ayoub , 2014 - 99 P. : facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry
Chronic infection with hepatitis C virus (HCV) is a huge problem both globally and at the level of the individual patient. The natural outcome and response to treatment in hepatitis C virus (HCV) infection varies between individuals. Our aim is to detect the Influence of Vitamin D receptor gene polymorphisms (BsmI) and (Fok1) and Vit. D level in the blood of chronic liver disease patients under treatment with interferon. Blood samples were taken from 103 patients who are suffering from chronic hepatitis C disease. They were divided into Respoders (n = 63)and Non- Responders (n = 40)according to their initial response to treatment with normalization of aminotransferases (ALT and AST) levels and clearance of the virus denoted by negative HCV - RNA by PCR after 6 months of receiving treatment
Hepatitis C Polymorphism Vitamin D