Gata 1 and gata 2 gene expression in myelodysplastic syndromes MDS /
Asmaa Ahmed AbdElAal
Gata 1 and gata 2 gene expression in myelodysplastic syndromes MDS / التعبير الجينى لجاتا 1 و جاتا 2 فى حالات متلازمة سوء النمو النخاعى Asmaa Ahmed AbdElAal ; Supervised Laila Abd El rahman Hegazi , Mervat Mohamed Wageh Mattar , Saher Kamal_Eldin Hussein - Cairo : Asmaa Ahmed AbdElAal , 2006 - 119p : ill ; 25cm
Thesis (PH.D.) - Cairo University - Faculty Of Medicine - Department Of Clinical and Chemical Pathology
GATA - 1 and GATA - 2 are 2 transcription factors playing important role in gene regulation during development and differentiation of haematopoietic cellsWhile GATA - 2 is essentially involved in the regulation of proliferation / self renewal of early haematopoietic cells , GATA - 1 is required for terminal differentiationSince inappropriate hematopoietic differentiation results in varying degree of myelodysplasia , which is the hallmark of MDS , GATA - 1 and GATA - 2 genes expression patterns were suspected to be associated with MDS
GATA - 1 GATA - 2 Transcription factors
Gata 1 and gata 2 gene expression in myelodysplastic syndromes MDS / التعبير الجينى لجاتا 1 و جاتا 2 فى حالات متلازمة سوء النمو النخاعى Asmaa Ahmed AbdElAal ; Supervised Laila Abd El rahman Hegazi , Mervat Mohamed Wageh Mattar , Saher Kamal_Eldin Hussein - Cairo : Asmaa Ahmed AbdElAal , 2006 - 119p : ill ; 25cm
Thesis (PH.D.) - Cairo University - Faculty Of Medicine - Department Of Clinical and Chemical Pathology
GATA - 1 and GATA - 2 are 2 transcription factors playing important role in gene regulation during development and differentiation of haematopoietic cellsWhile GATA - 2 is essentially involved in the regulation of proliferation / self renewal of early haematopoietic cells , GATA - 1 is required for terminal differentiationSince inappropriate hematopoietic differentiation results in varying degree of myelodysplasia , which is the hallmark of MDS , GATA - 1 and GATA - 2 genes expression patterns were suspected to be associated with MDS
GATA - 1 GATA - 2 Transcription factors