Steady - state serum levels of vascular cell adhesion molecule -1 in children with sickle cell disease : Relevance to stroke risk and disease severity /
Ahmed Ibrahim Amin Ibrahim
Steady - state serum levels of vascular cell adhesion molecule -1 in children with sickle cell disease : Relevance to stroke risk and disease severity / مستوى الجزىء الخلوى الالتصاقى رقم 1 فى الدم و علاقته بحدوث الجلطات المخية و شدة المرض فى الاطفال المرضى بأنيميا الخلايا المنجلية Ahmed Ibrahim Amin Ibrahim ; Supervised Mona Hassan Eltagui , Mona Kamal Elghamrawy , Foad Abdelmonem Abdallah - Cairo : Ahmed Ibrahim Amin Ibrahim , 2014 - 154 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics
Our study conducted on 85 patients with SCD aged 2 - 18 years, 8.4% of patients showed high risk study and 12.0% were conditional. One high risk patient had the qualifying velocity in ACA only. Regression analysis showed transfusion and HU dose protective against stroke. Mean VCAM level was 1438.12 ± 848.2 ng / ml and significantly higher than of normal population and higher in patient with normal TCD (P. 038). However, correlation of VCAM level with TAMMvel using showed + ve correlation with (P. 041). Levels were higher in HbSÝ subgroup, higher bilirubin level (and frequency of blood transfusion). In SS subgroup, VCAM level was significantly correlated with severity frequency (P . 001) and duration (P . 001) of VOCs. Level was lower with HU treatment P. 041
Sickle cell anaemia Stroke VCAM -1
Steady - state serum levels of vascular cell adhesion molecule -1 in children with sickle cell disease : Relevance to stroke risk and disease severity / مستوى الجزىء الخلوى الالتصاقى رقم 1 فى الدم و علاقته بحدوث الجلطات المخية و شدة المرض فى الاطفال المرضى بأنيميا الخلايا المنجلية Ahmed Ibrahim Amin Ibrahim ; Supervised Mona Hassan Eltagui , Mona Kamal Elghamrawy , Foad Abdelmonem Abdallah - Cairo : Ahmed Ibrahim Amin Ibrahim , 2014 - 154 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics
Our study conducted on 85 patients with SCD aged 2 - 18 years, 8.4% of patients showed high risk study and 12.0% were conditional. One high risk patient had the qualifying velocity in ACA only. Regression analysis showed transfusion and HU dose protective against stroke. Mean VCAM level was 1438.12 ± 848.2 ng / ml and significantly higher than of normal population and higher in patient with normal TCD (P. 038). However, correlation of VCAM level with TAMMvel using showed + ve correlation with (P. 041). Levels were higher in HbSÝ subgroup, higher bilirubin level (and frequency of blood transfusion). In SS subgroup, VCAM level was significantly correlated with severity frequency (P . 001) and duration (P . 001) of VOCs. Level was lower with HU treatment P. 041
Sickle cell anaemia Stroke VCAM -1