The possible protective effect of some medical plants extracts against drug induced liver dysfunction in albino rats /
Asmaa Mostafa Tawfek
The possible protective effect of some medical plants extracts against drug induced liver dysfunction in albino rats / التاثير الوقائى المحتمل لبعض مستخلصات النباتات الطبية ضد اعتلال الكبد المستحث بأحد العقاقير الطبية فى فئران التجارب البيضاء Asmaa Mostafa Tawfek ; Supervised Amr Saad Elsayed , Ayman Mohamed Badawi , Mohamed Ali Eldesoky - Cairo : Asmaa Mostafa Tawfek , 2015 - 151 P. : charts ; cm
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biochemistry
This work has been carried out in order to investigate the ameliorative effect of olive leaf and pomegranate peel in oxytetracycline (OTC)-induced liver injury in albino rats. The antioxidant potential was carried out using the ethanolic extract of olive leaf (OLE) and pomegranate peel (PPE). DPPH radical scavenging assay and total phenolic contents methods proved the antioxidant potency of OLE and PPE. In vitro studies using the different biochemical techniques, antioxidant parameters and the antimutagenic activity of the tested plants by DNA fragmentation assay proved that OTC caused a significant increase in all parameters concerned the liver toxicity while treatment of OLE and PPE caused an amliorative effect on this toxicity
Olive leaf Oxytetracycline Pomegranate
The possible protective effect of some medical plants extracts against drug induced liver dysfunction in albino rats / التاثير الوقائى المحتمل لبعض مستخلصات النباتات الطبية ضد اعتلال الكبد المستحث بأحد العقاقير الطبية فى فئران التجارب البيضاء Asmaa Mostafa Tawfek ; Supervised Amr Saad Elsayed , Ayman Mohamed Badawi , Mohamed Ali Eldesoky - Cairo : Asmaa Mostafa Tawfek , 2015 - 151 P. : charts ; cm
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biochemistry
This work has been carried out in order to investigate the ameliorative effect of olive leaf and pomegranate peel in oxytetracycline (OTC)-induced liver injury in albino rats. The antioxidant potential was carried out using the ethanolic extract of olive leaf (OLE) and pomegranate peel (PPE). DPPH radical scavenging assay and total phenolic contents methods proved the antioxidant potency of OLE and PPE. In vitro studies using the different biochemical techniques, antioxidant parameters and the antimutagenic activity of the tested plants by DNA fragmentation assay proved that OTC caused a significant increase in all parameters concerned the liver toxicity while treatment of OLE and PPE caused an amliorative effect on this toxicity
Olive leaf Oxytetracycline Pomegranate