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Role of respiratory syncytial virus and human metapneumovirus in severe lower respiratory tract infection in under 2years old children admitted to intensive care unit at pediatric cairo university hospital /

Radwa Wagih Abdelbaset Mahmoud

Role of respiratory syncytial virus and human metapneumovirus in severe lower respiratory tract infection in under 2years old children admitted to intensive care unit at pediatric cairo university hospital / دور الفيروس المخلوي التنفسي وفيروس الميتانيوم التنفسي قي الالتهاب التنفسي السفلي الشديد في الاطفال المصريين تحت سن سنتين المحجوزين في الرعاية المركزة في مستشفي الاطفال الجامعي- جامعة القاهرة Radwa Wagih Abdelbaset Mahmoud ; Supervised Heba Taher Othman ,Walaa ElSharany Abuelhamd , Dina Mohamed Hassan - Cairo : Radwa Wagih Abdelbaset Mahmoud , 2015 - 137 P. : facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Background: Viruses are the most important causative agents of acute lower respiratory tract infections (ALRI), ranked as the second leading cause of death and the primary cause of hospitalisation in children. Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) are among the commonest viral causes of severe ALRTI. Aim: To study the burden of both RSV and hMPV in causing severe ALRI in children less than 2years admitted to PICU at a tertiary care hospital. Setting and Design: Five months prospective observational study in a pediatric hospital of Cairo University. Material and Methods: Nasopharyngeal swabs were collected from children admitted into PICU with diagnosis of community-acquired ALRI who were aged 0-2 years. Samples were transported to the laboratory at (-80C) in viral transport media and processed for detection of RSV and hMPV using real-time polymerase chain reaction (RT-PCR)



Human metapneumovirus Respiratory syncytial virus Severe lower respiratory