Virulence factors of extended spectrum Beta-lactamase-producing gram-negative clinical isolates /
Ahmed Mohammed Abdelhaleem
Virulence factors of extended spectrum Beta-lactamase-producing gram-negative clinical isolates / عوامل الضراوة لبعض العزلات الاكلينيكية السالبة الجرام والمنتجة لإنزيمات البيتا لاكتميز الممتدة الطيف Ahmed Mohammed Abdelhaleem ; Supervised Magdy A. Amin , Ramy Karam Aziz - Cairo : Ahmed Mohammed Abdelhaleem , 2015 - 130 , 24 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology
The rapid emergence of microbial strains that are resistant to almost every existing antibiotic, often described as 2superbugs3, is a serious threat to human health, with the eventual risk of depletion of all antibiotic choices against some bacterial pathogens by the next decade. Escherichia coli (E.coli) is particularly known for its genomic plasticity and its subsequent ability to horizontally acquire novel genetic characters, including antibiotic resistance, especially in the hospital environment. Major outbreaks of extended spectrum beta lactamase-producing (ESBL) E.coli (ESBLEC) have been reported in Egypt and other countries. Because of the difficulty to track the spread of antibiotic resistance contributed by closely related genes, this study was designed to investigate the outbreaks of ESBL among E. coli clinical isolates. One hundred ninety eight clinical isolates were collected from the National Cancer Institute, Qasr El-Ainy, and Abu-El-Rish Children Hospital in Cairo-Egypt, and their antibiotic sensitivity was screened by the Kirby Bauer disk diffusion method.
ctx Extended spectrum New variants
Virulence factors of extended spectrum Beta-lactamase-producing gram-negative clinical isolates / عوامل الضراوة لبعض العزلات الاكلينيكية السالبة الجرام والمنتجة لإنزيمات البيتا لاكتميز الممتدة الطيف Ahmed Mohammed Abdelhaleem ; Supervised Magdy A. Amin , Ramy Karam Aziz - Cairo : Ahmed Mohammed Abdelhaleem , 2015 - 130 , 24 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology
The rapid emergence of microbial strains that are resistant to almost every existing antibiotic, often described as 2superbugs3, is a serious threat to human health, with the eventual risk of depletion of all antibiotic choices against some bacterial pathogens by the next decade. Escherichia coli (E.coli) is particularly known for its genomic plasticity and its subsequent ability to horizontally acquire novel genetic characters, including antibiotic resistance, especially in the hospital environment. Major outbreaks of extended spectrum beta lactamase-producing (ESBL) E.coli (ESBLEC) have been reported in Egypt and other countries. Because of the difficulty to track the spread of antibiotic resistance contributed by closely related genes, this study was designed to investigate the outbreaks of ESBL among E. coli clinical isolates. One hundred ninety eight clinical isolates were collected from the National Cancer Institute, Qasr El-Ainy, and Abu-El-Rish Children Hospital in Cairo-Egypt, and their antibiotic sensitivity was screened by the Kirby Bauer disk diffusion method.
ctx Extended spectrum New variants