The effect of curcumin on type 17 helper T cells in collagen-induced arthritis in rats /
Elshaimaa Mohsen Ibrahim Mostafa
The effect of curcumin on type 17 helper T cells in collagen-induced arthritis in rats / ثأثير الكركمين على نوع الخلايا تى 71 المساعدة في التهاب المفاصل المستحث بالكولاجين في الجرذان Elshaimaa Mohsen Ibrahim Mostafa ; Supervised Somaya Eldeeb , Amany Elwakkad , Abeer Badr - Cairo : Elshaimaa Mohsen Ibrahim Mostafa , 2014 - 224 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Zoology
Rheumatoid arthritis (RA) is one of the major human systemic autoimmune diseases, affecting approximately 1% of the world population, with unknown etiology attacking synovial joints, causing bone erosion, which leads to joint deformation, fractures and severe disability. For which there is no effective cure available. CIA was chosen as an animal model of RA as it produces many of the clinical and pathological features of human RA. Male albino rats were divided into 7 groups: N, D, A, Cb, Ca, M and CM. Treatments in groups Ca, M and CM were initiated from day 20 and continued till day 69. Blood samples were collected on days 0, 20, 41, 48, 61 and 69 post-induction, and serum levels of IL-17, IL-23, IL-27, IFN-y and TGF-ß were measured. Rats were sacrificed on the 69th day and thymus, lung, liver, spleen, kidney and hind paws were collected for histopathological examination
CIA MTX RA
The effect of curcumin on type 17 helper T cells in collagen-induced arthritis in rats / ثأثير الكركمين على نوع الخلايا تى 71 المساعدة في التهاب المفاصل المستحث بالكولاجين في الجرذان Elshaimaa Mohsen Ibrahim Mostafa ; Supervised Somaya Eldeeb , Amany Elwakkad , Abeer Badr - Cairo : Elshaimaa Mohsen Ibrahim Mostafa , 2014 - 224 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Zoology
Rheumatoid arthritis (RA) is one of the major human systemic autoimmune diseases, affecting approximately 1% of the world population, with unknown etiology attacking synovial joints, causing bone erosion, which leads to joint deformation, fractures and severe disability. For which there is no effective cure available. CIA was chosen as an animal model of RA as it produces many of the clinical and pathological features of human RA. Male albino rats were divided into 7 groups: N, D, A, Cb, Ca, M and CM. Treatments in groups Ca, M and CM were initiated from day 20 and continued till day 69. Blood samples were collected on days 0, 20, 41, 48, 61 and 69 post-induction, and serum levels of IL-17, IL-23, IL-27, IFN-y and TGF-ß were measured. Rats were sacrificed on the 69th day and thymus, lung, liver, spleen, kidney and hind paws were collected for histopathological examination
CIA MTX RA