Association between interleukin 17A and interleukin 17F gene polymorphisms and the susceptibility to acute myeloid leukemia in adult Egyptians /
Doaa Salah Mahmoud
Association between interleukin 17A and interleukin 17F gene polymorphisms and the susceptibility to acute myeloid leukemia in adult Egyptians / العلاقة بين التعدد الجيني لانترلوكين 17أ و انترلوكين 17ف وقابلية حدوث سرطان الدم النخاعي الحاد في المصريين البالغين Doaa Salah Mahmoud ; Supervised Manal Mohamed Wagdy Elmasry , Ahmed Mohamed Abdelhafez - Cairo : Doaa Salah Mahmoud , 2015 - 116 P. : charts ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
The current study aimed at defining the role of interleukin 17A(G197A) and interleukin 17F (A7488G) genetic polymorphisms as risk factors for AML in Egypt. The present study included 100 patients and 100 controls. Genotyping for the genes was done by PCR- RFLP technique. The study revealed that interleukin 17F polymorphic genotypes (AG/GG) were statistically significantly lower in cases than control. Interleukin 17A gene polymorphisms did not confer increased risk for acute myeloid leukemia
Acute myeloid leukemia Genetic polymorphisms Interleukin 17
Association between interleukin 17A and interleukin 17F gene polymorphisms and the susceptibility to acute myeloid leukemia in adult Egyptians / العلاقة بين التعدد الجيني لانترلوكين 17أ و انترلوكين 17ف وقابلية حدوث سرطان الدم النخاعي الحاد في المصريين البالغين Doaa Salah Mahmoud ; Supervised Manal Mohamed Wagdy Elmasry , Ahmed Mohamed Abdelhafez - Cairo : Doaa Salah Mahmoud , 2015 - 116 P. : charts ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
The current study aimed at defining the role of interleukin 17A(G197A) and interleukin 17F (A7488G) genetic polymorphisms as risk factors for AML in Egypt. The present study included 100 patients and 100 controls. Genotyping for the genes was done by PCR- RFLP technique. The study revealed that interleukin 17F polymorphic genotypes (AG/GG) were statistically significantly lower in cases than control. Interleukin 17A gene polymorphisms did not confer increased risk for acute myeloid leukemia
Acute myeloid leukemia Genetic polymorphisms Interleukin 17