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Comparative study between dexmedetomidine, fentanyl versus their combination as analgesic adjuvants to bupivacaine in spinal anesthesia in patients undergoing knee arthroscopy /

Mohamed Esmat Mohamed

Comparative study between dexmedetomidine, fentanyl versus their combination as analgesic adjuvants to bupivacaine in spinal anesthesia in patients undergoing knee arthroscopy / دراسة مقارنة بين عقار الديكسميدتومين وعقار الفنتانيل ومزيجهما معا كمسكن مساعد لعقار البوبيفكين فى التخدير النصفى للمرضى الذين يخضعون لمنظار ركبة جراحى Mohamed Esmat Mohamed ; Supervised Mohamed Elkhateb , Saad Elbasha , Hesham Abueldahab - Cairo : Mohamed Esmat Mohamed , 2015 - 137 P. : facsimiles ; 205cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anaesthesia

In The study included 45 patients randomized into three equal groups. Group D received 5 ogdexmedetomidine, group F received 25 og fentanyl and group DF received 5 ogdexmedetomidine plus 25 og fentanyl. These drugs were added to 2.5 ml hyperbaric bupivacaine 0.5% for all groups.intrathecaldexmedetomidine as an adjuvant to bupivacaine seems to be a good alternative to fentanyl for knee arthroscopy due to its intrathecal anesthetic and analgesic properties with minimal side effects. There is no need to add fentanyl to dexmedetomidineintrathecally; this combination was no better than dexmedetomidine alone in efficacy or safety



COX Dexmedetomidine NMDA