The value of using amantadine hydrochloride upon improving conscious level in isolated head trauma patients guided by glasgow coma scale and bispectral index /
Ahmed Sameer Saad Ibraheem
The value of using amantadine hydrochloride upon improving conscious level in isolated head trauma patients guided by glasgow coma scale and bispectral index / قيمة استخدام عقار الأمانتادين على تحسين درجة الوعي في مرضى إصابات الرأس المنعزلة استرشادا بمقياس جلاسجو لدرجة الوعي ومقياس ثنائي الطيف Ahmed Sameer Saad Ibraheem ; Supervised Omar Wagih Abass , Inas Mohamed Elghareeb Elshazly , Hisham Abdelwahab Abdelaziz Abueldahb. - Cairo : Ahmed Sameer Saad Ibraheem , 2015 - 86 Leaves : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anesthesia
We performed the current study to find out the effect of Amantadine upon rate of improvement of conscious level in patients with isolated head injuries undergoing surgical intervention. Patients in group 1 (n= 20) were given amantadine intraoperative at a dose of 100 mg IV infusion over 3 hours, then amantadine were given at a dose of 100 mg IV infusion over 3 hours every 12 hours for 7 days then was switched to tablet form at a dose of 300 mg per day divided into 3 equal doses, the 1st was given in the morning and the last before 5 o'clock PM. Patients in group 2 (n= 20) were given placebo instead at the same form and intervals. Glasgow coma scale and bispectral index readings were recorded at time of arrival, immediate post operative, 3days and 2 weeks post operative. We found that Glasgow coma scale rate of improvement in group1 was 4.53 ± 2.61and in group2 was 2.11 ± 2.81 which is statistically significant P value 0.014. We conclude from this study that the rate of improvement of patients given amantadine was significantly higher than those given placebo
Amantadine Bispectral index Glasgow coma scale
The value of using amantadine hydrochloride upon improving conscious level in isolated head trauma patients guided by glasgow coma scale and bispectral index / قيمة استخدام عقار الأمانتادين على تحسين درجة الوعي في مرضى إصابات الرأس المنعزلة استرشادا بمقياس جلاسجو لدرجة الوعي ومقياس ثنائي الطيف Ahmed Sameer Saad Ibraheem ; Supervised Omar Wagih Abass , Inas Mohamed Elghareeb Elshazly , Hisham Abdelwahab Abdelaziz Abueldahb. - Cairo : Ahmed Sameer Saad Ibraheem , 2015 - 86 Leaves : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anesthesia
We performed the current study to find out the effect of Amantadine upon rate of improvement of conscious level in patients with isolated head injuries undergoing surgical intervention. Patients in group 1 (n= 20) were given amantadine intraoperative at a dose of 100 mg IV infusion over 3 hours, then amantadine were given at a dose of 100 mg IV infusion over 3 hours every 12 hours for 7 days then was switched to tablet form at a dose of 300 mg per day divided into 3 equal doses, the 1st was given in the morning and the last before 5 o'clock PM. Patients in group 2 (n= 20) were given placebo instead at the same form and intervals. Glasgow coma scale and bispectral index readings were recorded at time of arrival, immediate post operative, 3days and 2 weeks post operative. We found that Glasgow coma scale rate of improvement in group1 was 4.53 ± 2.61and in group2 was 2.11 ± 2.81 which is statistically significant P value 0.014. We conclude from this study that the rate of improvement of patients given amantadine was significantly higher than those given placebo
Amantadine Bispectral index Glasgow coma scale