Heteroarylnitrilimines and related intermediates in the synthesis of heterocyclic compounds with expected biological activity /
Nora Ali Mohamed Ali Anter
Heteroarylnitrilimines and related intermediates in the synthesis of heterocyclic compounds with expected biological activity / ا ات ا و ا ا ت و ا ط Nora Ali Mohamed Ali Anter ; Supervised Hamdi M. Hassaneen , Sherif M. Sherif - Cairo : Nora Ali Mohamed Ali Anter , 2015 - 82 Leaves ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry
The present dissertation describes the utitity of heterocyclic hydrazonoyl halides 1A,B in the synthesis of a new enaminones 3A,B which used for the synthesis of various bipyrazole 8, 13, 14 and pyrazolopyridazine derivatives 10,15. A new 5- amino- 4- iminopyrazolo [3, 4- d] pyrimidine 18A,B was prepared and used in the synthesis of 1, 9- diarylpyrazolo [4,3 - e] 1, 2, 4- triazolo [1, 5- c] pyrimidine 19, 20, 21. Also, triazolo [4, 3- b] [1, 2, 4] triazin - 7- one derivatives 30 and spiropyrazolines 32 were prepared from reaction of heterocyclic hydrazonoyl halides 1A,B with 3- thioxo - 1, 2, 4- triazin - 5- ones 22 and 5- arylmethylene - 3- phenyl - 4- oxothiazole - 2- thione 31, respectively. The structures of the compounds were established on the basis of elemental and spectral analyses as well as their chemical reactions
Cycloaddition reactions Enaminones Hydrazonoyl halides
Heteroarylnitrilimines and related intermediates in the synthesis of heterocyclic compounds with expected biological activity / ا ات ا و ا ا ت و ا ط Nora Ali Mohamed Ali Anter ; Supervised Hamdi M. Hassaneen , Sherif M. Sherif - Cairo : Nora Ali Mohamed Ali Anter , 2015 - 82 Leaves ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry
The present dissertation describes the utitity of heterocyclic hydrazonoyl halides 1A,B in the synthesis of a new enaminones 3A,B which used for the synthesis of various bipyrazole 8, 13, 14 and pyrazolopyridazine derivatives 10,15. A new 5- amino- 4- iminopyrazolo [3, 4- d] pyrimidine 18A,B was prepared and used in the synthesis of 1, 9- diarylpyrazolo [4,3 - e] 1, 2, 4- triazolo [1, 5- c] pyrimidine 19, 20, 21. Also, triazolo [4, 3- b] [1, 2, 4] triazin - 7- one derivatives 30 and spiropyrazolines 32 were prepared from reaction of heterocyclic hydrazonoyl halides 1A,B with 3- thioxo - 1, 2, 4- triazin - 5- ones 22 and 5- arylmethylene - 3- phenyl - 4- oxothiazole - 2- thione 31, respectively. The structures of the compounds were established on the basis of elemental and spectral analyses as well as their chemical reactions
Cycloaddition reactions Enaminones Hydrazonoyl halides